Clinician (Oncology / Hematology)
Status: Open
- Pay
- $160–$200/hr
- Location
- Remote
- Employment type
- Contractor
- Openings
- 30
- Posted
- 2026-08-04
About this opportunity
Required skills
- clinical oncology
- clinical hematology
- clinical trial evaluation
- ctcae grading
- recist
- lugano criteria
- imwg criteria
- iwcll criteria
- eln criteria
- outcome endpoint analysis (orr, dor, pfs, os, mrd)
- dose escalation assessment
- adverse event grading and attribution
- regulatory document review (csrs, protocols, investigator brochures, safety narratives, dsm/idmc materials)
- benefit-risk analysis
- clinical reasoning
- structured written communication
- guideline-based documentation
- explaining complex information to non-clinical audiences
- medical monitoring
- committee participation (idmc, dsmb, adjudication, independent review)
- peer-reviewed publication
- attention to detail
- critical thinking
- problem identification and resolution
What you'll do
- Author and review evaluation tasks that require nuanced clinical judgment, leveraging Clinical Study Reports, periodic safety reports, and regulatory correspondence in oncology and haematology.
- Assess the clinical defensibility of efficacy and safety conclusions, ensuring endpoints and effect sizes reflect true clinical significance.
- Apply advanced judgment to dose escalation, dose-limiting toxicity, modifications, adverse event grading and attribution, and the coherence of patient narratives.
- Evaluate benefit-risk reasoning, scrutinizing the durability of conclusions in light of new events, and the realism of described management strategies.
- Identify and flag content that is clinically implausible or internally inconsistent, distinguishing these from legitimate clinical variation.
- Provide structured, guideline-based written rationales that clearly explain the validity or limitations of clinical interpretations for a non-clinical audience.
Preferred qualifications
- Specialist registration or board certification in medical oncology and/or haematology, with 5+ years of post-training clinical experience.
- Direct involvement in clinical trials as investigator, sub-investigator, or sponsor-side medical monitor, safety physician, or clinical development physician.
- Proficiency with CTCAE grading, relevant response criteria (RECIST, Lugano, IMWG, IWCLL, ELN), and outcome endpoints (ORR, DoR, PFS, OS, MRD).
- Hands-on experience with trial documents such as protocols, investigator brochures, CSRs, safety narratives, or DSMB/IDMC materials.
- Demonstrated excellence in written communication, with clear, structured explanations of clinical reasoning tailored for non-clinical readers.
- Previous roles in medical monitoring or as medical director on oncology or haematology programmes, and committee participation (IDMC, DSMB, adjudication, or independent review committees).
- Peer-reviewed publication record or authorship on clinical trial manuscripts, with any exposure to AI-assisted clinical review tools seen as a plus.